I also use a mix of a sync'n'charge cable with a full charge every now and then.
Back when I had my Asus a730w (in which the battery emptied in the blink of an eye), I made a little research and it seemed to be a general best practice that these Li-Ion batteries that our pdas have should be "trained" to stay charged, i.e., charge it often and try to avoid big charge/discharge cycles.
So, I usually charge my Loox while sync'ing which means that generally I only let it discharge to 60% or 70%.
Every now and then, I force a bigger cycle (to have the best of both worlds, just in case

) and let it discharge to about 30% and then charge it in the cradle.
Of course, like on all battery discussions, this is somewhat subjective, but as I said, from what I've read, "training" your battery to remain topped while every now and then mixing it with a higher discharge cycle seems to produce good results.
Having said that, from my tests, my Loox's battery still performs extremelly close now to what it did when I purchased it about 8 months ago.